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With prolonged exposure or high doses, it transitions to a Phase II block, involving both pre- and post-synaptic effects, including impaired acetylcholine release (autoreceptor inhibition) and open-channel block

Do not use if you are sensitive to melatonin or have been diagnosed with a sleep disorder

3G10 was conjugated to HRP using the EZ-Link Plus Activated Peroxidase Kit (Thermo Scientific, Cat# 31489) according to the manufacturers instructions

Most patients complete their treatment course within 2 to 3 months, though some continue with maintenance sessions

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